Vemulapalli., Krishna C.Lahr, Rachel E.Lee, Christopher J.Abdullah, NoorRex, Douglas K.2022-01-272022-01-272022-01Vemulapalli., K. C., Lahr, R. E., Lee, C. J., Abdullah, N., & Rex, D. K. (2022). Yield of a second right colon examination during colonoscopy after a first examination using a mucosal exposure device. Gastrointestinal Endoscopy, 95(1), 149-154.e1. https://doi.org/10.1016/j.gie.2021.07.0120016-5107https://hdl.handle.net/1805/27584Background and Aims Double right colon examination during colonoscopy has been advocated to reduce the risk of interval cancer in the right colon. Whether 2 examinations are necessary when the first examination is performed with a mucosal exposure device is uncertain. We documented the rates of missed adenomas, sessile serrated lesions, and hyperplastic polyps after an initial right colon examination by a high-level detector using a mucosal exposure device. Methods At a single tertiary hospital outpatient practice, we prospectively collected data on the yield of a second examination of the right colon after an initial examination by a single high-detecting colonoscopist using a mucosal exposure device. Results During the study period, 1331 eligible consecutive patients underwent colonoscopy. Right colon adenoma, sessile serrated lesion, and hyperplastic polyp miss rates were 15.8%, 14.1%, and 16.7%, respectively. Four percent of patients had adenomas detected in the right colon only with a second examination. Conclusions A second examination of the right colon is warranted, even when using a distal mucosal exposure device to perform colonoscopy.en-USPublisher Policycolonoscopyright colonrisk of interval cancerright colon examinationArticle