Starr, Michelle C.Altemose, KathleenParsley, JessalynnCater, Daniel T.Hains, David S.Soranno, Danielle E.2023-11-072023-11-072024-01Starr, M. C., Altemose, K., Parsley, J., Cater, D. T., Hains, D. S., & Soranno, D. E. (2024). Safety and timeliness of telemedicine initiation of continuous kidney replacement therapy. Pediatric Nephrology, 39(1), 325-329. https://doi.org/10.1007/s00467-023-06036-3https://hdl.handle.net/1805/36949Background During the COVID-19 pandemic, some continuous kidney replacement therapy (CKRT) initiations were transitioned to telemedicine to improve the timeliness of initiation, and minimize COVID-19 transmission. While telemedicine would appear acceptable for many clinical settings, safety and timeliness of telemedicine CKRT initiation is undescribed. Methods We conducted a single-center retrospective cohort study of pediatric patients on CKRT from January 2021–September 2022. Information on patient characteristics and CKRT therapy was extracted from the electronic health record. Multidisciplinary team provider attitudes and perspectives were assessed using survey. Results During the study period, there were 101 CKRT circuit initiations in patients not previously receiving CKRT, with 33% (33/101) initiated by telemedicine. There were no differences in patient characteristics, including age, weight at initiation, severity of illness, nor degree of fluid overload between the in-person and telemedicine initiation cohorts. CKRT telemedicine initiations were timelier, occurring on average 3.0 h after decision to initiate therapy compared to 5.8 h for all in-person CKRT starts (p < 0.001) and 5.5 h for night and weekend in-person starts (p < 0.001). Complications did not differ between telemedicine and in-person starts (15% vs. 15%, p = 0.99) and initial circuit life was similar. There were no differences in likelihood of death or duration of CKRT therapy. Telemedicine initiations were widely acceptable to multidisciplinary providers. Conclusion In appropriately selected patients, telemedicine initiation of CKRT is a timely and safe option. Further standardization of telemedicine initiation of CKRT should be considered to improve the timely delivery of CKRT and may improve nephrology workforce wellness.en-USPublisher Policytelemedicinedialysispediatrickidney replacement therapyArticle