Carpenter, KendalIqbal, AymanSingh, RomilDeepika, KeertiKoritala, ThoyajaJain, NiteshAlur, Ram SanjeevAdhikari, RameshMellekate, Vishwas S.2023-05-302023-05-302022-02-07Carpenter K, Iqbal A, Singh R, et al. COVID-19 Infection and Guillain-Barre Syndrome: A Case Series. Cureus. 2022;14(2):e21998. Published 2022 Feb 7. doi:10.7759/cureus.21998https://hdl.handle.net/1805/33354The coronavirus disease 2019 (COVID-19) pandemic brought about an unprecedented time. Multiple systemic complications have been recognized with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) as it can do much more than affect the respiratory system. One of the intriguing neurological complications is Guillain-Barre syndrome (GBS). We reviewed three cases in which patients presented with GBS following COVID-19 infection. All three cases had positive lumbar puncture results with albumino-cytological dissociation. Each patient was treated with plasmapheresis and improved clinically. Although an exact causal relationship between COVID-19 and GBS cannot be drawn from this case series alone, it signifies the importance of this complication. It warrants further studies to establish the causal relationship. One should have a high suspicion for acute inflammatory demyelinating polyneuropathy (AIDP) in patients presenting with acute onset of ascending weakness following COVID-19 infection.en-USAttribution 4.0 InternationalAcute inflammatory demyelinating polyradiculoneuropathyAlbuminocytologic dissociationCovid-19Cytokine stormGullian-barre syndromeMyasthenia gravisNeurological complicationArticle