Mez, JesseMarden, Jessica R.Mukherjee, ShubhabrataWalter, StefanGibbons, Laura E.Gross, Alden L.Zahodne, Laura B.Gilsanz, PaolaBrewster, PaulNho, KwangsikCrane, Paul K.Larson, Eric B.Glymour, M. Maria2018-03-142018-03-142017-08-24Mez, J., Marden, J. R., Mukherjee, S., Walter, S., Gibbons, L. E., Gross, A. L., … Glymour, M. M. (2017). Alzheimer’s disease genetic risk variants beyond APOE ε4 predict mortality. Alzheimer’s & Dementia : Diagnosis, Assessment & Disease Monitoring, 8, 188–195. https://doi.org/10.1016/j.dadm.2017.07.0022352-8729https://hdl.handle.net/1805/15539• A genetic risk score from 21 non-APOE late-onset Alzheimer's disease risk variants predicts mortality. • The genetic risk score likely confers risk for mortality through its effect on dementia incidence. • Late-onset Alzheimer's disease risk loci effect estimates from genome-wide association unlikely suffer from selection bias.en-USAttribution-NonCommercial-NoDerivs 3.0 United StatesAPOEAdult Changes in Thought (ACT)Alzheimer's diseaseCohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE)Collider stratification biasGenetic risk scoreenome-wide association study (GWAS)Health and Retirement Study (HRS)LongevityMortalitySelection biasSurvival analysisSurvivor biasArticle