Mar, Philip L.Barmeda, MamtaStucky, Marcelle A.Devabahktun, Subodh R.Garlie, JasonMiller, John M.Jain, Rahul2020-07-212020-07-212020-02-18Mar, P. L., Barmeda, M., Stucky, M. A., Devabahktuni, S. R., Garlie, J., Miller, J. M., & Jain, R. (2020). Unique features of epicardial ventricular arrhythmias/premature ventricular complexes ablated from coronary venous system in veteran population. Indian pacing and electrophysiology journal, 20(3), 97–104. https://doi.org/10.1016/j.ipej.2020.02.001https://hdl.handle.net/1805/23307Introduction: Ventricular arrhythmias/premature ventricular complexes (VA/PVCs) that can be ablated from within the coronary venous system (CVS) have not been described in the United States Veterans Health Administration (VHA) population. We retrospectively studied the VA/PVCs ablations that were performed in the VHA population. Methods: Data from 42 consecutive patients who underwent VA/PVCs ablation at Veterans Affairs Hospital, Indianapolis, IN, with 44 VA/PVCs was included in the study. Patients were divided into two groups (CVS group [n = 10], and non-CVS group [n = 32]) based on where the earliest pre-systolic activation was seen with >95% pacematch. Results: The mean age in CVS group was 65 ± 8 years versus 64 ± 12 years (p = 0.69) in non-CVS group. Overall there was a statistically significant reduction in PVC burden post ablation (27.7% (pre-ablation) versus 4.7% (post-ablation). In the 10 patients in the CVS group, either ablation or catheter-related mechanical trauma resulted in complete (n = 6 [60%]) or partial (n = 4 [40%]) long-term suppression of VA/PVCs. Right bundle branch block-type VA/PVC (9/11: 82%) was the most common morphology in the CVS group, whereas in the non-CVS group, this type was seen in only 3/33 (9%). The CVS group (25% of total VA/PVCs) had shorter activation time compared to non CVS group. Conclusion: In our experience VA/PVCs with electrocardiograms suggestive of epicardial origin can often be safely and successfully ablated within the coronary venous system. These arrhythmias have unique features in Veterans patient population.en-USAttribution-NonCommercial-NoDerivatives 4.0 InternationalPremature ventricular complexVentricular arrhythmiasRadiofrequency ablationCoronary venous systemArticle