Maddatu, JudithAnderson-Baucum, EmilyEvans-Molina, Carmella2017-06-082017-06-082017-06Maddatu, J., Anderson-Baucum, E., & Evans-Molina, C. (2017). Smoking and the Risk of Type 2 Diabetes. Translational Research. http://dx.doi.org/10.1016/j.trsl.2017.02.004https://hdl.handle.net/1805/12917Despite accumulating evidence demonstrating strong epidemiologic and mechanistic associations between cigarette smoking, hyperglycemia, and the development of type 2 diabetes, tobacco abuse has not been uniformly recognized as a modifiable risk factor in diabetes prevention or screening strategies. In this review, we highlight population-based studies that have linked cigarette smoking with an increased risk of type 2 diabetes and summarize clinical and preclinical studies offering insight into mechanisms through which cigarette smoking and nicotine exposure impact body composition, insulin sensitivity, and pancreatic β cell function. Key questions for future studies are identified and strategies for smoking cessation as a means to decrease diabetes risk are discussed.enPublisher Policydiabetes mellituscigarette smokingnicotineArticle