Pryce, Benjamin R.Wang, David J.Zimmers, Teresa A.Ostrowski, Michael C.Guttridge, Denis C.2024-09-182024-09-182023Pryce BR, Wang DJ, Zimmers TA, Ostrowski MC, Guttridge DC. Cancer cachexia: involvement of an expanding macroenvironment. Cancer Cell. 2023;41(3):581-584. doi:10.1016/j.ccell.2023.02.007https://hdl.handle.net/1805/43383Advanced cancers often present with the cachexia syndrome that impacts peripheral tissues, leading to involuntary weight loss and reduced prognosis. The central tissues undergoing depletion are skeletal muscle and adipose, but recent findings reveal an expanding tumor macroenvironment involving organ crosstalks that underlie the cachectic state.en-USPublisher PolicyCachexiaSkeletal muscleNeoplasmsArticle