Hays, Travis R.Mund, Julie A.Liu, ZiyueCase, JamieIngram, David A.Gupta, Samir K.2016-08-122016-08-122015-04-15Hays, T. R., Mund, J. A., Liu, Z., Case, J., Ingram, D. A., & Gupta, S. K. (2015). Endothelial Colony Forming Cells and Inflammatory Monocytes in HIV. Journal of Acquired Immune Deficiency Syndromes (1999), 68(5), 550–553. http://doi.org/10.1097/QAI.00000000000005061944-7884https://hdl.handle.net/1805/10689The relationships between HIV infection, monocyte activation, and endothelial colony-forming cells (ECFCs) are unknown. We compared ECFC, intermediate monocytes (CD14 CD16), and nonclassical monocytes (CD14 CD16) levels in HIV-infected participants virologically suppressed on antiretroviral therapy, HIV-infected treatment-naive participants, and HIV-uninfected healthy controls. ECFC levels were significantly higher in the HIV-infected virologically suppressed group compared with the uninfected controls. CD14 CD16 percentages (but not CD14 CD16 cells) were significantly higher in both HIV-infected groups vs. uninfected controls. In the HIV-infected groups, ECFCs and CD14 CD16 intermediate monocytes were significantly and inversely correlated. Lower availability of ECFCs may partly explain the relationship between greater intermediate monocytes and atherosclerosis in HIV.en-USPublisher PolicyEndothelial Progenitor CellsphysiologyHIV InfectionsimmunologypathologyMonocytesArticle