Singleton, CarolynCarter, AllieBaker, BrittanyJones, EmmaGreen, KelseyLammert, CraigNephew, Lauren D.2025-06-022025-06-022024Singleton, C., Carter, A., Baker, B., Jones, E., Green, K., Lammert, C., & Nephew, L. D. (2024). Low socioeconomic status exacerbates unmet health-related needs in patients with autoimmune hepatitis. Alimentary Pharmacology & Therapeutics, 60(10), 1339–1350. https://doi.org/10.1111/apt.18235https://hdl.handle.net/1805/48512Diminished quality of life has been well characterized in patients with autoimmune hepatitis (AIH); however, the full spectrum of unmet needs is unclear. We hypothesized that there is a high burden of health-related unmet needs in patients with AIH, and this burden differs by socioeconomic status (SES). Methods Members of the Autoimmune Hepatitis Association were invited online and by email to complete a modified version of the Systemic Lupus Erythematosus Patient Needs Questionnaire. Demographic and clinical data were also captured. Low SES was defined as annual household income <30 k, education level below high school, or moderate–high concern for transportation, food or housing. Multivariable logistic regression assessed the association between unmet health-related needs and SES. Results There were 433 participants; 89.8% identified as women, 16.2% lived outside the US, and 25.6% were classified as low SES. Over 70% of respondents reported at least one moderate–high need in the health-related unmet need domains. In multivariable logistic regression, patients in the low-SES group reported significantly higher odds of unmet needs compared to the moderate–high-SES group: for adequate information about side effects (OR 1.64, 95% CI 1.06–2.53, p = 0.026), opportunity to speak with others with AIH (OR 2.34, 95% CI 1.50–3.66, p < 0.001), healthcare professionals acknowledging patient emotions (OR 2.41, 95% CI 1.56–3.74, p < 0.001) and being taken seriously by medical providers (OR 2.09, 95% CI 1.34–3.28, p = 0.001). There is a high burden of health-related unmet needs in all patients with AIH that is exacerbated by low SES.en-USAutoimmune hepatitisSocioeconomic statusArticle