AlJishi, Jumana MansourAlhajjaj, Alya HassanAlkhabbaz, Fatimah LateefAlAbduljabar, Taaweel HussainAlsaif, AhmadAlsaif, HussainAlomran, Kawther SaeedAljanobi, Ghada AliAlghawi, ZainabAlsaif, MohammedAl-Tawfiq, Jaffar A.2021-02-122021-02-122021-01-01AlJishi, J. M., Alhajjaj, A. H., Alkhabbaz, F. L., AlAbduljabar, T. H., Alsaif, A., Alsaif, H., Alomran, K. S., Aljanobi, G. A., Alghawi, Z., Alsaif, M., & Al-Tawfiq, J. A. (2021). Clinical characteristics of asymptomatic and symptomatic COVID-19 patients in the Eastern Province of Saudi Arabia. Journal of Infection and Public Health, 14, 6–11. https://doi.org/10.1016/j.jiph.2020.11.0021876-035X1876-0341https://hdl.handle.net/1805/25218Background: The first case of COVID-19 infection in Saudi Arabia was reported in Qatif on March 2nd, 2020. Here, we describe the clinical characteristics of the initial COVID-19 patients in that area. Methods: This is an observational study describing the clinical presentation, radiographic and laboratory data of COVID-19 cases. Results: From March 1st, 2020 to April 5th, 2020 we identified a total of 82 adult COVID-19 patients. The median age of the patients was 50 years, with a range of 30 to 60 years and most of patients were female 54 (65.9%). Of all the patients, 29 (35.4%) were contacts and 43 (52.4%) were returning travelers, mainly from Iraq (65% of the total returning travelers). Comorbidities were present in 50% of patients, G6PD deficiency in 33%, hypertension in 27%, and diabetes mellitus in 26%. Chest radiographs were abnormal in 46% of symptomatic and 15.5% of asymptomatic patients (P value = 0.0035). Of all patients, 4 (4.87%) required intensive care admission. There was no significant difference in time to negative RT-PCR with mean days to negativity of 13.6 and 16.9 for asymptomatic and symptomatic group, respectively (P value = 0.42). Conclusions: In the initial Epicenter of the COVID-19 in Saudi Arabia, the majority of the patients were asymptomatic and were returning travelers. Comorbidities were present in nearly half of the patients.en-USIUPUI Open Access PolicyAttribution-NonCommercial-NoDerivatives 4.0 InternationalCOVID-19Observational StudyClinical CharacteristicsComorbiditiesSaudi ArabiaArticle