Waning, David L.Mohammad, Khalid S.Guise, Theresa A.2015-09-022015-09-022013-10-14Waning, D. L., Mohammad, K. S., & Guise, T. A. (2013). Cancer-associated osteoclast differentiation takes a good look in the miR(NA)ror. Cancer Cell, 24(4), 407–409. http://doi.org/10.1016/j.ccr.2013.10.001https://hdl.handle.net/1805/6712Tumor-bone cell interactions are critical for the development of metastasis-related osteolytic bone destruction. In this issue of Cancer Cell, Ell and colleagues show how a discrete miRNA network regulates osteoclastogenesis during breast cancer bone metastasis. A signature of upregulated miRNAs may have diagnostic and therapeutic implications for bone metastases.en-USPublisher PolicyAnimalsBone Neoplasms/pathologyHumansMicroRNAs/metabolismOsteoclasts/cytologyTumor Markers, Biological/metabolismArticle