Sonn, Kevin A.Meneghini, R. Michael2022-04-062022-04-062020-01-09Sonn KA, Meneghini RM. Early failure of sequentially annealed polyethylene in total knee arthroplasty. Arthroplast Today. 2020 Jan 9;6(1):18-22. doi: 10.1016/j.artd.2019.12.005. PMID: 32211470; PMCID: PMC7083714.https://hdl.handle.net/1805/28409Improvements in the processing of polyethylene have led to a dramatic reduction in wear rates in total hip arthroplasty. This led to the adoption of modern highly cross-linked polyethylene in total knee arthroplasty (TKA). However, the differences in modes of wear and failure between total hip arthroplasty and TKA have tempered expectations regarding similar decreases in polyethylene-related complications in TKA. We present a case of early catastrophic failure of a modern sequentially irradiated and annealed highly cross-linked polyethylene insert only 5 years after contemporary cementless TKA.en-USAttribution-NonCommercial-NoDerivatives 4.0 InternationalBiomaterialsEarly failurePolyethylene wearRevisionSequentially annealedTotal knee arthroplastyArticle