Williams, James C.Lingeman, James E.Coe, Fredric L.Worcester, Elaine M.Evan, Andrew P.2016-05-312016-05-312015-01Williams, J. C., Lingeman, J. E., Coe, F. L., Worcester, E. M., & Evan, A. P. (2015). Micro-CT imaging of Randall’s plaques. Urolithiasis, 43 Suppl 1, 13–17. http://doi.org/10.1007/s00240-014-0702-zhttps://hdl.handle.net/1805/9698Micro-computed tomographic imaging (micro-CT) provides unprecedented information on stone structure and mineral composition. High-resolution micro-CT even allows visualization of the lumens of tubule and/or vessels within Randall's plaque, on stones or in papillary biopsies, thus giving a non-destructive way to study these sites of stone adhesion. This paper also shows an example of a stone growing on a different anchoring mechanism: a mineral plug within the lumen of a Bellini duct (BD plug). Micro-CT shows striking structural differences between stones that have grown on Randall's plaque and those that have grown on BD plugs. Thus, Randall's plaque can be distinguished by micro-CT, and this non-destructive method shows great promise in helping to elucidate the different mechanisms by which small stones are retained in the kidney during the development of nephrolithiasis.NephrolithiasisImagingKidney stonesComputed tomographyArticle