Laulhé, SébastienBlackburn, J. MilesRoizen, Jennifer L.2019-01-182019-01-182017-06-29Laulhé, S., Blackburn, J. M., & Roizen, J. L. (2017). Exhaustive Suzuki-Miyaura reactions of polyhalogenated heteroarenes with alkyl boronic pinacol esters. Chemical communications (Cambridge, England), 53(53), 7270-7273.https://hdl.handle.net/1805/18194A novel Suzuki-Miyaura protocol is described that enables the exhaustive alkylation of polychlorinated pyridines. This method facilitates a formal synthesis of normuscopyridine and the rapid assembly of a dumbbell shaped portion of a [2]rotaxane.en-USPublisher PolicySuzuki-Miyaura ReactionsPolyhalogenated heteroarenesAlkyl boronic pinacol estersStable heteroaryl chloridesCross-coupling reactionCommercially available reagentsReduced toxicityFormal synthesis of normuscopyridineArticle