Slaven, James E.Haas, David W.Liu, ZiyueStein, James H.Brown, Todd T.Gupta, Samir K.2019-07-122019-07-122019-05Slaven, J., Haas, D., Liu, Z., Stein, J., Brown, T., & Gupta, S. (2019). GCH1 haplotypes and cardiovascular risk in HIV. Aids. https://doi.org/10.1097/QAD.0000000000002263https://hdl.handle.net/1805/19868Heightened systemic inflammation contributes to cardiovascular (CVD) events in people living with HIV (PLWH), though not all PLWH develop CVD, thus suggesting a genetic modifying role. We examined GCH1 polymorphisms, which have been associated with reduced endothelial function in European populations with CVD and increased inflammation, in a racially diverse cohort of U.S. PLWH initiating antiretroviral therapy (ART). GCH1 polymorphisms differed by race and were not associated flow-mediated dilation or carotid intima media thickness before or after 48 weeks of ART.enPublisher PolicyHIV-1endothelial functionGCH1Article