Vitalpur, GirishEsquivel, AnnKloepfer, Kirsten M.Slaven, James E.Leickly, Frederick E.2016-08-312016-08-312016Vitalpur, G., Esquivel, A., Kloepfer, K. M., Slaven, J. E., & Leickly, F. E. (2016). Multisystem reactions during egg oral food challenges may be associated with less severe reactions on initial presentation. Allergy, Asthma, and Clinical Immunology : Official Journal of the Canadian Society of Allergy and Clinical Immunology, 12, 21. http://doi.org/10.1186/s13223-016-0125-11710-1484https://hdl.handle.net/1805/10811In this study, we assessed whether multisystem reactions to egg and extensively-heated (EH) egg during OFCs were associated with a history of multisystem reactions. Records of children, who underwent OFC to egg or EH egg over a five-year period were reviewed. Of the 120 challenges, 26 (21.67 %) failed, with 38.4 % (10/26) having multisystem reactions. Of the 13 who had multisystem reactions on initial presentation, only two (15.4 %) had a similar OFC outcome. Eighty percent (8/10) of those who had a multisystem OFC reaction had a less severe initial presentation. Initial and OFC multisystem reactions were not associated with each other.en-USAttribution 3.0 United StatesEgg allergyExtensively heated (EH) egg allergyOral food challenge (OFC)Reaction severityType of reactionArticle