Martin, Sarah E.Al-Khatib, Sohaib M.Turner, Michael S.Douglas-Akinwande, Annette C.Hattab, Eyas M.2023-03-092023-03-092010-03Martin SE, Al-Khatib SM, Turner MS, Douglas-Akinwande AC, Hattab EM. A 41-year-old woman with von Hippel-Lindau and a cerebellar lesion. Brain Pathol. 2010;20(2):511-514. doi:10.1111/j.1750-3639.2009.00363.xhttps://hdl.handle.net/1805/31763A 41-year-old woman with a 12-year history of von Hippel-Lindau disease presented with progressive quadriparesis and difficulty swallowing. MRI revealed a well-circumscribed, partially cystic cerebellar neoplasm, consistent with hemangioblastoma. The tumor was resected and the diagnosis of hemangioblastoma confirmed. Embedded within the hemangioblastoma was a small focus of metastatic renal cell carcinoma (RCC). RCC metastatic to a CNS hemangioblastoma is the second most common type of tumor-to-tumor metastasis, which may be due to a number of factors. Proper immunostaining panels are required to clearly identify these cases since both tumor may have similar histology.en-USAttribution 4.0 InternationalBrain neoplasmsRenal cell carcinomaCerebellar neoplasmsHemangioblastomaKidney neoplasmsvon Hippel-Lindau diseaseArticle