Kohne, Joseph G.MacLaren, GraemeRider, EricaCarr, BenjaminMallory, PalenGebremariam, AchamFriedman, Matthew L.Barbaro, Ryan P.2024-06-202024-06-202022-04Kohne, J. G., MacLaren, G., Rider, E., Carr, B. D., Mallory, P., Gebremariam, A., Friedman, M. L., & Barbaro, R. P. (2022). Tracheostomy Practices and Outcomes in Children During Respiratory Extracorporeal Membrane Oxygenation. Pediatric Critical Care Medicine, 23(4), 268. https://doi.org/10.1097/PCC.0000000000002902https://hdl.handle.net/1805/41666Objectives: Children receiving prolonged extracorporeal membrane oxygenation (ECMO) support may benefit from tracheostomy during ECMO by facilitating rehabilitation; however the procedure carries risks, especially hemorrhagic complications. Knowledge of tracheostomy practices and outcomes of ECMO-supported children who undergo tracheostomy on ECMO may inform decision-making. Design: Retrospective cohort study Setting: ECMO centers contributing to the Extracorporeal Life Support Organization (ELSO) Registry Patients: Children birth to 18 years who received ECMO support for 7 days or greater for respiratory failure from January 1st 2015 to December 31st 2019. Interventions: None Measurements and Main Results: 3685 children received at least seven days of ECMO support for respiratory failure. The median duration of ECMO support was 13.0 days (IQR 9.3-19.9), and in-hospital mortality was 38.7% (1426/3685). A tracheostomy was placed during ECMO support in 94/3685 (2.6%). Of those who received a tracheostomy on ECMO, the procedure was performed at a median 13.2 days (IQR 6.3-25.9) after initiation of ECMO. Surgical site bleeding was documented in 26% of children who received a tracheostomy (12% after tracheostomy placement). Among children who received a tracheostomy, the median duration of ECMO support was 24.2 days (IQR 13.0-58.7); in-hospital mortality was 30/94 (32%). Those that received a tracheostomy before 14 days on ECMO were older (median age 15.8 years (IQR 4.7-15.5) versus 11.7 years (IQR 11.5-17.3); p-value=0.002) and more likely to have been supported on VV-ECMO (84% vs 52%, p=0.001). Twenty-two percent (11/50) of those who received a tracheostomy before 14 days died in the hospital, compared to 19/44 (43%) of those who received a tracheostomy at 14 days or later (p=0.03). Conclusions: Tracheostomies during ECMO were uncommon in children. One in four patients who received a tracheostomy on ECMO had surgical site bleeding. Children who had tracheostomies placed after 14 days were younger and had worse outcomes, potentially representing tracheostomy as a “secondary” strategy for prolonged ECMO support.en-USPublisher PolicyTracheostomyExtracorporeal Membrane OxygenationRespiratory Distress SyndromeAcuteRespiratory InsufficiencyCritical Care OutcomesHealth Services ResearchArticle