Wedi, EdrisOrlandini, BeatriceGromski, MarkJung, Carlo Felix MariaTchoumak, IrinaBoucher, StephanieEllenrieder, VolkerHochberger, Jürgen2018-07-242018-07-242018-01Wedi, E., Orlandini, B., Gromski, M., Jung, C. F. M., Tchoumak, I., Boucher, S., … Hochberger, J. (2018). Full-Thickness Resection Device for Complex Colorectal Lesions in High-Risk Patients as a Last-Resort Endoscopic Treatment: Initial Clinical Experience and Review of the Current Literature. Clinical Endoscopy, 51(1), 103–108. http://doi.org/10.5946/ce.2017.093https://hdl.handle.net/1805/16788The full-thickness resection device (FTRD) is a novel endoscopic device approved for the resection of colorectal lesions. This case-series describes the device and its use in high-risk patients with colorectal lesions and provides an overview of the potential indications in recently published data. Between December 2014 and September 2015, 3 patients underwent endoscopic full thickness resection using the FTRD for colorectal lesions: 1 case for a T1 adenocarcinoma in the region of a surgical anastomosis after recto-sigmoidectomy, 1 case for a non-lifting colonic adenoma with low-grade dysplasia in an 89-year old patient and 1 for a recurrent adenoma with high-grade dysplasia in a young patient with ulcerative rectocolitis who was under immunosuppression after renal transplantation. Both technical and clinical success rates were achieved in all cases. The size of removed lesions ranged from 9 to 30 mm. Overall, the most frequent indication in the literature has been for lifting or non-lifting adenoma, submucosal tumors, neuroendocrin tumors, incomplete endoscopic resection (R1) or T1 carcinoma. Colorectal FTRD is a feasible technique for the treatment of colorectal lesions and represents a minimally invasive alternative for either surgical or conventional endoscopic resection strategies.en-USAttribution-NonCommercial 3.0 United StatesColonoscopyColorectal neoplasmsFull-thickness resection deviceOver-the-scope-clipArticle