Karahan, HandeDabin, Luke C.Tate, Mason D.Kim, Jungsu2024-08-122024-08-122021Karahan H, Dabin LC, Tate MD, Kim J. MicroRNAs on the move: microRNAs in astrocyte-derived ApoE particles regulate neuronal function. Neuron. 2021;109(6):907-909. doi:10.1016/j.neuron.2021.02.021https://hdl.handle.net/1805/42720In this issue of Neuron, Li et al. (2021) demonstrate that ApoE lipoprotein particles shuttle miRNAs from astrocytes to neurons, leading to inhibition of cholesterol biosynthesis and an increase in histone acetylation in neurons.en-USPublisher PolicyAcetylationApolipoproteins EAstrocytesCholesterolMicroRNAsNeuronsArticle