Salama, RashaZhou, Jiehao2016-05-312016-05-312016-01Salama, R., & Zhou, J. (2016). Vacuolated lymphocytes signifying a metabolic disorder in an infant with developmental delay. Clinical Case Reports, 4(1), 99–100. http://doi.org/10.1002/ccr3.447https://hdl.handle.net/1805/9689Metabolic disorders sometimes cause accumulation of metabolic byproducts which are manifested as cytoplasmic vacuoles in lymphocytes. We report the case of an infant with final diagnosis of GM1 gangliosidosis who initially presented with developmental delay and peripheral blood vacuolated lymphocytes. Blood film review is recommended in children suspicious for metabolic disorders.Attribution-NonCommercial-NoDerivs 3.0 United StatesMetabolic disorderperipheral blood smearvacuolated lymphocyteArticle