Johnson, Bailey N.Hadad, IvanHassanein, Aladdin H.Fisher, Carla S.2025-04-222025-04-222025-03-27Johnson BN, Hadad I, Hassanein AH, Fisher CS. Risk-Reducing Gender-Affirming Mastectomy: Unique Considerations in BRCA. Clin Case Rep. 2025;13(4):e70336. Published 2025 Mar 27. doi:10.1002/ccr3.70336https://hdl.handle.net/1805/47266Individualized breast cancer risk assessment should be considered for transmasculine patients pursuing gender-affirming mastectomy to identify and educate high-risk patients about the option for risk-reduction gender-affirming mastectomy. This reduces oncologic risk while achieving the desired cosmetic outcome, ultimately enhancing preventative care provided to an underserved population.en-USAttribution-NonCommercial-NoDerivatives 4.0 InternationalBRCABreast cancerCancer screeningMastectomyTransgenderTransmasculineArticle