Chioncel, OvidiuCollins, Sean P.Ambrosy, Andrew P.Pang, Peter S.Antohi, Elena-LauraIliescu, Vlad AntonMaggioni, Aldo P.Butler, JavedMebazaa, Alexandre2019-09-052019-09-052018-07Chioncel, O., Collins, S. P., Ambrosy, A. P., Pang, P. S., Antohi, E. L., Iliescu, V. A., … Mebazaa, A. (2018). Improving Postdischarge Outcomes in Acute Heart Failure. American journal of therapeutics, 25(4), e475–e486. doi:10.1097/MJT.0000000000000791https://hdl.handle.net/1805/20817The global burden that acute heart failure (AHF) carries has remained unchanged over the past several decades (1). European registries (2–5) showed that 1-year outcome rates remain unacceptably high (Table 1) and confirm that hospitalization for AHF represents a change in the natural history of the disease process(6). As patients hospitalized for HF have a bad prognosis, it is crucial to utilize hospitalization as an opportunity to: 1) assess the individual components of the cardiac substrate; 2) identify and treat comorbidities; 3) identify early, safe endpoints of therapy to facilitate timely hospital discharge and outpatient follow-up; and 4) implement and begin optimization guideline-directed medical therapies (GDMTs). As outcomes are influenced by many factors, many of which are incompletely understood, a systematic approach is proposed that should start with admission and continues through post-discharge (7).en-USPublisher PolicyAcute diseaseDiureticsHeart failureHemodynamicsVascular diseasesArticle