Ando, MasatoshiFerreira-Zandoná, Andrea G.Eckert, George J.Zero, Domenick T.Stookey, George K.2017-11-212017-11-212017-03Ando, M., Ferreira-Zandoná, A. G., Eckert, G. J., Zero, D. T., & Stookey, G. K. (2017). Pilot clinical study to assess caries lesion activity using quantitative light-induced fluorescence during dehydration. Journal of Biomedical Optics, 22(3), 035005-035005. https://doi.org/10.1117/1.JBO.22.3.035005https://hdl.handle.net/1805/14629This study aimed to evaluate the ability of quantitative light-induced fluorescence (QLF) to assess caries lesion activity using visual examination (VE) as the gold standard. Twenty-four visible white spot lesions on buccal surfaces were examined from 23 children, ages 9 to 14 years. At baseline, the surface was hydrated with water, and thereafter, it was dehydrated with continuous compressed air during image acquisition. QLF images were acquired at 0 (baseline), 5, and 15 s. QLF variables [ QLF V : fluorescence loss ( Δ F ), lesion size (S), Δ Q : Δ F × S ] was recorded. Changes-in- QLF V per second ( Δ QLF V ) were determined: Δ QLF V = ( QLF VN − QLF V Baseline ) / N , where N indicates dehydration time. One experienced dentist conducted VE independently using a dental unit’s light, compressed air, and explorer.enPublisher Policyclinical studycaries lesion activitydiagnosticsArticle