Stram, Amanda R.Kesler, Kenneth A.2022-04-082022-04-082020-10Stram, A. R., & Kesler, K. A. (2020). Mediastinal Germ Cell Tumors: Updates in Diagnosis and Management. Surgical Oncology Clinics of North America, 29(4), 571–579. https://doi.org/10.1016/j.soc.2020.06.0051558-5042https://hdl.handle.net/1805/28453Primary mediastinal nonseminomatous germ cell tumors represent a rare but important malignancy that occurs in otherwise young and healthy patients. Treatment is challenging and involves cisplatin-based chemotherapy followed by surgery to remove residual disease. Avoiding bleomycin-containing chemotherapy in the treatment of primary mediastinal nonseminomatous germ cell tumors is important. Prechemotherapy and postchemotherapy pathology as well as postoperative serum tumor markers are independent predictors of long-term survival.en-USPublisher PolicyChemotherapyCombined Modality TherapyMediastinal NeoplasmsMediastinal tumorsThoracic surgeryArticle