Ichkhanian, YervantChaudhary, Ammad J.Veracruz, NicoletteFaisal, Muhammad SalmanPeller, MatthewKushnir, VladimirDaugherty, T. TylerGenere, Juan ReyesPawa, RishiPawa, SwatiAhmed, WafaaHuggett, Matthew T.Paranandi, BharatAparicio, José RamónMartínez-Moreno, BelénNimri, FaisalAshraf, TahaAlluri, SpandanaObri, MarkDang, DuyenSingla, SumitPiraka, CyrusZuchelli, Tobias2025-02-282025-02-282025Ichkhanian, Y., Chaudhary, A. J., Veracruz, N., Faisal, M. S., Peller, M., Kushnir, V., Daugherty, T. T., Genere, J. R., Pawa, R., Pawa, S., Ahmed, W., Huggett, M. T., paranandi, B., Aparicio, J. R., Martínez-Moreno, B., Nimri, F., Ashraf, T., Alluri, S., Obri, M., … Zuchelli, T. (2025). Endoscopic Ultrasound-Guided Drainage of Intra-Abdominal Abscess Using 15-mm vs. 10-mm Lumen-Apposing Metal Stents: An International Case-Matched Study. Gastrointestinal Endoscopy. https://doi.org/10.1016/j.gie.2025.01.002https://hdl.handle.net/1805/46148Background and Aims Efficacy and safety of EUS-guided placement of lumen-apposing metal stents (LAMS) has been reported yet advantage of using 15-mm LAMS over 10-mm LAMS yet to be explored. Methods International, retrospective, case-matched study of patients with intra-abdominal abscess who underwent EUS-guided drainage with 15-mm (case) and 10-mm (control) LAMS between 03/2019 and 09/2022. Results 51 patients underwent EUS-guided drainage using LAMS [15-mm 29 (57%), 10-mm 22 (43%)]. The most common location of the abscess was peri-pancreatic 43%. Technical success rate was achieved in 97% of cases and 100 % of controls (p=0.412), while clinical success was achieved in 98% and 96%, respectively, (OR 1.3; p=0.089). AE occurred in 7.8% of the cases. Patients with 15-mm LAMS underwent fewer total endoscopic procedures (mean 2.5 vs.3.6; P < 0.023). Conclusion Both sizes showed comparable clinical success and safety profiles, with a significant trend of the need for fewer endoscopic procedures with the 15-mm LAMS.enPublisher Policylumen-apposing metal stentsEUS-guided placementintra-abdominal abscessArticle