Villagomez, Fabian R.Lang, JulieNunez-Avellaneda, DanielBehbakht, KianDimmick, Hannah L.Webb, Patricia G.Nephew, Kenneth P.Neville, MargaretWoodruff, Elizabeth R.Bitler, Benjamin G.2025-02-282025-02-282025Villagomez FR, Lang J, Nunez-Avellaneda D, et al. Claudin-4 Stabilizes the Genome via Nuclear and Cell-Cycle Remodeling to Support Ovarian Cancer Cell Survival. Cancer Res Commun. 2025;5(1):39-53. doi:10.1158/2767-9764.CRC-24-0558https://hdl.handle.net/1805/46136High-grade serous ovarian carcinoma is marked by chromosomal instability, which can serve to promote disease progression and allow cancer to evade therapeutic insults. The report highlights the role of claudin-4 in regulating genomic instability and proposes a novel therapeutic approach to exploit claudin-4-mediated regulation.en-USAttribution 4.0 InternationalCell cycleClaudin-4Genomic instabilityOvarian neoplasmsArticle