Cai, QingchunXu, Yan2017-04-102017-04-102015-01Cai, Q., & Xu, Y. (2015). The microenvironment reprograms circuits in tumor cells. Molecular & Cellular Oncology, 2(1), e969634. http://doi.org/10.4161/23723548.2014.969634https://hdl.handle.net/1805/12219In the course of multistep oncogenesis, initially normal cells acquire several new functions that render them malignant. We have recently demonstrated that the peritoneal microenvironment promotes resistance to anoikis in ovarian cancer cells by reprogramming SRC/AKT/ERK signaling and metabolism. These findings have prognostic and therapeutic implications.en-USAttribution-NonCommercial 3.0 United StatesSRCanoikis resistancecell survivalfloating cellsglycolysismicroenvironmentovarian cancerThe microenvironment reprograms circuits in tumor cellsArticle